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ONCOLOGIST
CARDIOLOGIST AND CARDIOVASCULAR SURGEON
GERIATRIC PHYSICIAN
PAIN MANAGEMENT PHYSICIAN
FOR THE PRIMARY CARE PHYSICIAN
INTERNIST
FAMILY PRACTICE PHYSICIAN
GYNECOLOGIST

 

Exercise improves functional fitness (flexibility, coordination, agility, strength and endurance, and cardiorespiratory endurance) and overall psychological well-being.

 

FOR THE ONCOLOGIST

Exercise and Conditions Related to Cancer and Cancer Treatment 

Fatigue remains the most frequently reported symptom of individuals with cancer, and is experienced by the majority of individuals receiving treatment for cancer. Fatigue has been described as

  • lacking energy

  • feeling exhausted

  • being unable to concentrate

  • feeling lethargic

  • lacking motivation

  • feelings of sleepiness, depression, and weakness

 

 

Cancer patient exercisers also reported a significantly improved quality of lifecompared to non-exercisers. The women who walked regularly adapted better to physical symptoms of chemotherapy, physical functioning, and psychosocial changes. They experienced consistent and progressive improvement during the course of chemotherapy, while the women who did not exercise got progressively weaker.
Women with breast cancer often gain as much as 5.5-13.6 pounds during adjuvant chemotherapy. Researchers have found that exercise can assist women with breast cancer in

 

  • maintaining body weight  

  • reducing body fat mass while receiving adjuvant therapy

 

Disease and cancer treatment-related side effects such as decreased energy level, muscle weakness, and declines in functional status and body mass have been well documented.  Additionally, there is evidence that regular physical activity or exercise can

  • decrease emotional stress

  • decrease blood pressure

  • decrease  the duration of neutropenia and thrombocytopenia

  • decrease pain

  • increase quality of life and

  • improve the maximal oxygen uptake during exertion, sleep patterns, and cognition

  •  

Therefore, education concerning activity and exercise should be included as part of routine health care for cancer patients.

 

FOR THE CARDIOLOGIST AND CARDIOVASCULAR SURGEON 

The cardiovascular and pulmonary systems respond to an acute bout of aerobic exercise by augmenting oxygen delivery to active skeletal muscle in an attempt to meet the energy requirements for a given level of physical stress. The capacity to increase oxygen delivery and utilization in response to aerobic exercise is dependent on several factors, including age, gender, fitness level, genetic variability, and disease status. 


Benefits Associated With Chronic Aerobic Exercise
 

 

 

 

 

 

 

 

 

 

 

 

 



For individuals in the high-risk or cardiovascular disease populations, moderate aerobic activity of any type has numerous health- related benefits.


Physical activity and health guidelines state that, for healthy adults (18-65 years of age),

  • the minimum aerobic exercise training goal is 30 minutes of continuous activity at a moderate intensity (i.e., brisk walking or similar activity corresponding to an intensity of approximately 3-6 METs)

  • 5 days per week or 20 minutes of continuous activity at a vigorous intensity (i.e., jogging or approximately >6 METs) 3 days per week.

 

Achievement of the 30-minute minimum duration goal may also be attained by accumulating bouts of aerobic exercise lasting at least 10 minutes throughout the day. 
Duration and intensity goals are similar for older healthy adults (>65 years of age),although

  • the threshold distinguishing between moderate- and vigorous- intensity exercise is likely to be lower than 6 METs for most individuals older than 65

  • recommended duration goal for moderate-intensity exercise is also the same for patients diagnosed with cardiovascular disease and heart failure

  • significant health benefits have been observed in individuals transitioning from a sedentary lifestyle to some level of physical activity that does not reach minimal goals (i.e., 45-150 minutes of brisk walking per week)

 

 

Surpassing the minimal recommendations (i.e., 30-60 minutes of aerobic exercise on most if not all days of the week and/or increasing the time spent performing vigorous aerobic exercise) produces greater health-related benefits.

 

FOR THE GERIATRIC PHYSICIAN 

Frail elders often have chronic illnesses,

 

  • osteoarthritis

  • hypertension

  • diabetes

  • peripheral vascular disease

 

 

 

Exercise is a proven means of achieving nonpharmacologic benefits, even at an advanced age. Exercise has been shown to enhance the quality of life for these elders.
The outcomes for studies of exercise in community-based frail elders include notably improved sleep derived from a modest aerobic exercise routine.  Many exercise studies reporting effectiveness have centered on disease states. Osteoarthritis is a major morbidity factor for frail elders for which exercise is a specific therapeutic intervention. Exercise intervention trials for knee osteoarthritis have shown significant reductions in disability using resistance training that focused on increasing muscle strength and modest aerobic exercise that centered on motion. The positive effects of either exercise modality speaks to the positive effects that any form of exercise can have if sustained even for a relatively short time. Specifically, for underlying conditions such as osteoarthritis, increased mobilization of the affected joints, when done in a safe manner, has resulted in pain reduction and enhanced mobility. 
The many physiologic advantages of

 

  • preventing cardiovascular disease

  • reducing insulin resistance

  • reducing blood pressure

  • improving hyperlipidemia

 

 

in the general population can also benefit frail elders. Most medical conditions, however, are treated with pharmacotherapy for maximal improvement. Interventions directed toward improving functional capabilities, such as

  • avoiding falls

  • increasing upper extremity range of motion (which enhances dressing and bathing)

 

would have a more direct impact on the daily well-being of frail elders. 
Regular exercise has been shown to provide such psychological benefits as

  • preserving cognitive function

  • alleviating depression

  •  improving a sense of personal control and self-efficacy

 

Strength training has been shown to improve mood significantly and reduce symptoms of anxiety. 
Physicians can effectively promote exercise as a therapeutic intervention for their frail elderly patients. It is essential that physicians enthusiastically discuss exercise on a regular basis. Exercise continues to be an underused therapeutic intervention. Theincreased vitality, strength, flexibility, balance, and general sense of well-beingthat can be achieved through this intervention will reward patient and physician alike.

 

FOR THE PAIN MANAGEMENT PHYSICIAN 

Modest Exercise Helps Chronic Pain Patients 
A frequent comorbid condition of chronic pain is profound physical deconditioning, which results from inactivity. Exercise produces significant immediate antidepressant and anxiolytic effects. The research suggests that relatively modest exercise leads to improved mood and physical capacity, which has further implications for mortality risk. Exercise is a safe, cost-free, nonpharmacologic strategy for immediately reducing depression and anxiety

 

FOR THE PRIMARY CARE PHYSICIAN, INTERNIST, FAMILY PRACTICE PHYSICIAN, GYNECOLOGIST

Mortality, longevity, and quality of life are the most critical issues facing America’s aging population. Aging is also usually associated with musculoskeletal degeneration. The degeneration of aging is associated with loss of muscle mass, decrease in proprioception, and strength. Proprioception is the ability to

  • accelerate

  • decelerate

  • stabilize

 

the extrinsic and intrinsic forces affecting one’s body. The most significant forms of musculoskeletal degeneration include

  • Osteoporosis: The decrease in bone mass density leads to 1.5 million fractures annually.  Only 20% of these patients ever return to normal functional status.  The combination of exercise which can increase bone mass density and training which stresses prevention of falls are best.

  • Osteoarthritis: Research demonstrates that osteoarthritis leads to decrease in strength and proprioception.  Patients with osteoarthritis exhibit increased inhibition of knee extensor musculature which is critical to ambulation.  Patients with moderate inhibition after a four week training regimen which included proprioception demonstrated a decrease in inhibition and increase in muscle strength.

  • Low back pain:   Patients with low back pain have a decrease in ability to balance on one foot which is crucial to efficient ambulation. These patients also have been shown to have ineffective coupling of pelvic musculature or core which leads to altered gait patterns. Strengthening of core musculature has been shown to increase strength and decrease low back pain.

  • Obesity: 50% of Americans are over weight.  For patients not involved in exercise there is a

    • 15% decrease in  fat free mass after age 30

    • Loss of 5 pounds of muscle per decade and simultaneous addition of 15 pounds of fat

 

 

This sarcopenia leads to age related decrease in strength, energy levels and basal metabolic rate. Research has shown a correlation between the weight of an individual and functional gait capacity.

Osteoporosis, osteoarthritis, low back pain and obesity lead to a decrease in functional capacity. The most critical component of functional capacity is the ability to walk. Many patients who have restrictions on the ability to walk resort to assistive devices including wheel chairs and motorized scooter.  This often accelerates degenerative processes leading to an increased risk of falling.  Many of these degenerative processes can either be slowed or reversed with proprioceptive, strength, resistance, and cardiovascular exercise and training.

 

Camille Williams MD is a retired Emeritus Facial Plastic and Reconstructive Surgeon. She is board certified in Head and Neck Surgery. Dr Williams is a graduate of the University of California San Francisco Medical School.  Before attending Medical School, Dr Camille Williams was a Nutritionist at St Luke’s Hospital and taught Home Economics at the college level.  She is a certified personal trainer with the National Academy of Sports Medicine.  Dr Camille Williams is currently the CEO of the Orinda Health and Fitness Center, a full service online health and fitness center with exercise training, diet advice, meal planning, grocery shopping assistance, and with access to an extensive health and fitness library. She also serves as a medical consultant to social security administration on disability. Camille Williams MD also has an MBA from St Mary’s College.

 

REFERENCES

Constance Visovsky PhD, RN, ACNP; Colleen Dvorak BSN, RN, OCN. (2005) Exercise and Cancer Recovery 
 

Online Journal of Issues in Nursing

rvine, D., Vincent, L., Graydon, J. E., Bubela, N., & Thompson, L. (1994). The prevalence and correlates of fatigue in patients receiving treatment with chemotherapy and biotherapy: A comparison with the fatigue experienced by healthy individuals. Cancer Nursing, 17(5), 367-378

(Winningham et al., 1994). Winningham, M. (1983). Effects of a bicycle ergometry program on functional capacity and feelings of control in women with breast cancer.Unpublished Doctoral Dissertation, The Ohio State University.


Winningham, M., & McVicar, M. (1988). The effect of aerobic exercise on patient reports of nausea. Oncology Nursing Forum, 15(4), 447-450. 


Winningham, M.L., MacVicar, M.G., Bondoc, M., Anderson, J.L., & Minton, J.P. (1989). Effect of aerobic exercise on body weight and composition in patients with breast cancer on adjuvant chemotherapy. Oncology Nursing Forum, 16(5), 683-689. 


Winningham, M, Nail, L., Burke, M., Brophy, L., Cimprich, B., Jones, L. S. et al. (1994). Fatigue and the cancer experience: The state of the knowledge. Oncology Nursing Forum, 21, 23-36 Schwartz, A. L. (1998). Patterns of exercise and fatigue in physically active cancer survivors. Oncology Nursing Forum, 25(3), 485-491. Schwartz, A. L. (2000). Exercise and weight gain in breast cancer patients receiving chemotherapy. Cancer Practice, 8(5), 231-237. Schwartz, A. L., Meek, P. M., Nail, L. M., Fargo, J., Lundquist, M., Donofrio, M. et al. (2002). Measurement of fatigue. Determining minimally important clinical differences. Journal of Clinical Epidemiology, 55(3), 239-244.

 

Ross Arena, PhD; Jonathan Myers, PhD; Marco Guazzi, MD, PhD (2008). The Clinical Significance of Aerobic Exercise Testing and Prescription: From Apparently Healthy to Confirmed Cardiovascular Disease.American Journal of Lifestyle Medicine

 

Physical activity and public health: updated recommendation for adults from the American College of Sports Medicine and the American Heart Association. Circulation. 2007;116:1081-1093.

Physical activity and public health in older adults: recommendation from the American College of Sports Medicine and the American Heart Association. Circulation. 2007;116:1094-105.

 

Thompson PD, Buchner D, Pina IL, et al. Exercise and physical activity in the prevention and treatment of atherosclerotic cardiovascular disease: a statement from the Council on Clinical Cardiology (Subcommittee on Exercise, Rehabilitation, and Prevention) and the Council on Nutrition, Physical Activity, and Metabolism (Subcommittee on Physical Activity). Circulation. 2003;107:3109-3116

 

Pina IL, Apstein CS, Balady GJ, et al. Exercise and heart failure: a statement from the American Heart Association Committee on Exercise, Rehabilitation, and Prevention.Circulation. 2003;107:1210-1225

 

John M. Heath, MD, and Marian R. Stuart, PhD (6/27/2002). Prescribing Exercise for Frail Elders.Journal of the American Board of Family Medicine

 

King AC, Oman RF, Brassington GS, Bliwise DL, Haskell WL. Moderate-intensity exercise and self-rated quality of sleep in older adults. A randomized controlled trial.JAMA 1997;277:32-7.

Recommendations for the medical management of osteoarthritis of the hip and knee: 2000 update. American College of Rheumatology Subcommittee on Osteoarthritis Guidelines. Arthritis Rheum 2000;43:1905-15.

 

Van Baar ME, Dekker J, Oostendorp RA, et al. The effectiveness of exercise therapy in patients with osteoarthritis of the hip or knee - a randomized controlled trial. J Rheumatol 1998;25:2432-9. 


Minor MA. Exercise in the management of osteoarthritis of the knee and hip. Arthritis Care Res 1994;7:198-204.

 

Green J, McKenna F, Redferm EJ, Chamberlain MA. Home exercises are as effective as outpatient hydrotherapy for osteoarthritis of the hip. Br J Rheumatol 1993;32:812-5.

Ettinger WH Jr. Physical activity, arthritis, and disability in older people. Clin Geriatr Med 1998;14:633-40. 


King AC, Haskell WL, Young DR, Oka RK, Stefanick ML. Long-term effects of varying intensities and formats of physical activity on participation rates, fitness, and lipoproteins in men and women aged 50-65 years. Circulation 1995;91:2596-604

Exercise and physical activity for older adults. American College of Sports Medicine.Med Sci Sports Exerc 1998;30:992-1008.

 

Doyle, Stephanie. Modest Exercise Helps Chronic Pain Patients; American Academy of Pain Medicine (AAPM) 24th Annual Meeting.  Medscape Medical News

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